VISDB Viral Integration Site DataBase

VIS ID

TVIS10005978

Fusion event

HBV-NCKAP1 integration

Validated

No

Detection method

PCR and Ultra-deep sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Start

2334

Orient

-

Integrated sequence

GAGAAACTGTTCTTGAGTATTTGGTGTCTTTTGGAGTGTGGATTCGCACTCCTCCCGCTTACAGACCACCAAATGCCCCTATCTTATCAACACTTCCGGA| |AACTACTGTTGTTAGACGACGAGGCAGGTCCCCTAGAAGAAGAACTCCCTCGCCTCGCAGACGAAGGTCTCAATCGCCGCGTCGCAGAAGATCTCAATCT

Chromosome

chr2

Cytoband

q32.1

Reference genome

Start

End

183872194/183007466 (Hg38)

Orient

-

Location type

Intron

Target gene

miRNAs that regulate target gene

hsa-mir-155-5p ; hsa-mir-142-3p ; hsa-mir-30a-5p ; hsa-mir-18b-5p ; hsa-mir-132-3p ; hsa-mir-4459 ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-1273e ; hsa-mir-582-5p ; hsa-mir-101-3p ; hsa-mir-8085 ; hsa-mir-6731-5p ; hsa-mir-6878-5p ; hsa-mir-25-5p ; hsa-mir-658 ; hsa-mir-655-5p ; hsa-mir-6087 ; hsa-mir-4537 ; hsa-mir-1273f ; hsa-mir-4708-5p ; hsa-mir-6088 ; hsa-mir-4770 ; hsa-mir-143-3p ; hsa-mir-219b-3p ; hsa-mir-1247-3p ; hsa-mir-6871-5p ; hsa-mir-302f ; hsa-mir-6828-5p ; hsa-mir-922 ; hsa-mir-6838-5p ; hsa-mir-497-5p ; hsa-mir-424-5p ; hsa-mir-195-5p ; hsa-mir-16-5p ; hsa-mir-15b-5p ; hsa-mir-15a-5p ; hsa-mir-548e-5p ; hsa-mir-6818-3p ; hsa-mir-593-3p ; hsa-mir-6895-3p ; hsa-mir-629-3p ; hsa-mir-498 ; hsa-mir-6867-3p ; hsa-mir-4713-5p ; hsa-mir-6783-3p ; hsa-mir-1343-3p ; hsa-mir-23b-5p ; hsa-mir-23a-5p ; hsa-mir-4284 ; hsa-mir-6829-3p ; hsa-mir-6791-3p ; hsa-mir-1304-3p ; hsa-mir-1281 ; hsa-mir-6742-3p ; hsa-mir-6852-5p ; hsa-mir-939-3p ; hsa-mir-4485-5p ; hsa-mir-6890-3p ; hsa-mir-1200 ; hsa-mir-3653-5p ; hsa-mir-544b ; hsa-mir-4324 ; hsa-mir-660-3p ; hsa-mir-7108-3p ; hsa-mir-4258 ; hsa-mir-335-3p ; hsa-mir-1305 ; hsa-mir-576-5p ; hsa-mir-4775 ; hsa-mir-5681b ; hsa-mir-95-5p ; hsa-mir-3163 ; hsa-mir-590-3p ; hsa-mir-3662 ; hsa-mir-4684-5p ; hsa-mir-3675-3p ; hsa-mir-6771-3p ; hsa-mir-548ay-3p ; hsa-mir-548at-3p ; hsa-mir-548as-3p ; hsa-mir-548t-3p ; hsa-mir-548ap-3p ; hsa-mir-548aa ; hsa-mir-548c-3p ; hsa-mir-34c-3p ; hsa-mir-1972 ; hsa-mir-383-5p ; hsa-mir-4650-5p ; hsa-mir-4772-5p ; hsa-mir-20a-3p ; hsa-mir-3913-3p ; hsa-mir-4732-3p ; hsa-mir-489-3p ; hsa-mir-544a ; hsa-mir-6719-3p ; hsa-mir-942-5p

Nearest miRNA

hsa-mir-10b/Upstream/1701814; hsa-mir-1244-1/Downstream/1371509;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/140101, chr2-CpG: 98/Downstream/30208

Junction sequence