Basic Information
VIS ID
TVIS10005995
Fusion event
HBV-chr3 integration
Validated
No
Detection method
PCR and Ultra-deep sequencing
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
1832
Orient
-
Integrated sequence
GGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCACCTCT| |GCCTAATCATCTCATGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTATAAAGAATTTGGAGC
Host Sequence
Chromosome
chr3
Cytoband
q26.2
Reference genome
End
170704275/170986486 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-let-7g/Upstream/563324; hsa-mir-1224/Downstream/120178;
Nearby gene
RNU1-70P(+8384) ;
Upstream sequence
aataaatgtcttatcaagtaaatggttagctgtgagtttatgtttaataattgaaaattatgtcattATAAATAATTTTAATGGTACACATAACCAGTTA
Downstream sequence
tctacttttgcactcaattatcaatatgtccagacataggattctagattgaaaatggtttttcttcagaatttcttcagaaggcatttctcctcagctt
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).
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