Basic Information
VIS ID
TVIS10006009
Fusion event
HBV-chr5 integration
Validated
No
Detection method
PCR and Ultra-deep sequencing
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
2332
Orient
-
Integrated sequence
AAGAGAAACTGTTCTTGAGTATTTGGTGTCTTTTGGAGTGTGGATTCGCACTCCTCCCGCTTACAGACCACCAAATGCCCCTATCTTATCAACACTTCCG| |GAAACTACTGTTGTTAGACGACGAGGCAGGTCCCCTAGAAGAAGAACTCCCTCGCCTCGCAGACGAAGGTCTCAATCGCCGCGTCGCAGAAGATCTCAAT
Host Sequence
Chromosome
chr5
Cytoband
q14.1
Reference genome
End
78428205/79132382 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-10397/Upstream/6253719; hsa-mir-103a-1/Downstream/3707773;
Nearby gene
BHMT(-92) ;
Upstream sequence
atgagcaatgtggatatcatattttgggtgttacgtgtgcattaggaaggctgcatttgtgttccgagcctgcagttggaccttgcaatgcagccccaag
Downstream sequence
aacctacttcacaagtatgctggaattttaaaggagCAGGTGGCAGTATTTAAAAGGAaaagaggccctactggctctttctggagagccagtcagggaa
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).
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