Fusion event
HBV-chr9 integration
Detection method
PCR and Ultra-deep sequencing
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Integrated sequence
CCGACCACGGGGCGCACCTCTCTTTACGCGGTCTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGA| |GACCACCGTGAACGCCCACCAGGTCTTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAA
End
37092071/37092074 (Hg38)
Nearest miRNA
hsa-mir-101-2/Upstream/198543; hsa-let-7a-1/Downstream/3836936;
Upstream sequence
gaggttgcagtgagctgagattgcgccactgcactcagcctgggcaacaagagtgagactccatctcaaaaaaaaaaaaaaaaaaaaaaaaaCTTTTTCT
Downstream sequence
ACATGTACATAACAGTTTTAGATACAATTTAACAGGATGGAGAACTCATCTAGAGGCAGTTGCTGAATTCCTGACGTTTATTAGGCACTCAACCAAGACT
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).