Basic Information
VIS ID
TVIS10006020
Fusion event
HBV-chr9 integration
Validated
No
Detection method
PCR and Ultra-deep sequencing
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
1612
Orient
+
Integrated sequence
CCGACCACGGGGCGCACCTCTCTTTACGCGGTCTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGA| |GACCACCGTGAACGCCCACCAGGTCTTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAA
Host Sequence
Chromosome
chr9
Cytoband
p13.2
Reference genome
End
37092071/37092074 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-101-2/Upstream/198543; hsa-let-7a-1/Downstream/3836936;
Nearby gene
EBLN3P(-1673) ;
Upstream sequence
gaggttgcagtgagctgagattgcgccactgcactcagcctgggcaacaagagtgagactccatctcaaaaaaaaaaaaaaaaaaaaaaaaaCTTTTTCT
Downstream sequence
ACATGTACATAACAGTTTTAGATACAATTTAACAGGATGGAGAACTCATCTAGAGGCAGTTGCTGAATTCCTGACGTTTATTAGGCACTCAACCAAGACT
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).
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