Basic Information
VIS ID
TVIS10006021
Fusion event
HBV-LOC107987084 integration
Validated
No
Detection method
PCR and Ultra-deep sequencing
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
29861854
Virus Sequence
Virus name
HBV
Reference genome
AP011098
Start
1823
Orient
+
Integrated sequence
TAAGGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACTTT| |TTCACCTCTGCCTAATCATCTCATGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTATAAAGA
Host Sequence
Chromosome
chr9
Cytoband
q21.31
Reference genome
GRCh37/hg19
Start
83479989/80865074 (Hg38)
End
83479989/80865074 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC107987084
Nearest miRNA
hsa-mir-101-2/Upstream/10054990; hsa-let-7a-1/Downstream/3104674;
Nearest TSS
ENST00000422679/Upstream/834495; ENST00000413050/Downstream/6221;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/1291429, chr9-CpG: 255/Downstream/822150
Junction sequence
G
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).
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