Basic Information
VIS ID
TVIS10006051
Fusion event
HBV-FIRRE integration
Validated
No
Detection method
PCR and Ultra-deep sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
29861854
Virus Sequence
Virus name
HBV
Reference genome
AP011098
Start
816
Orient
-
Integrated sequence
CCACTGTTTGGCTTTCAGTTATATGGATGATGTGGTATTGGGGGCCAAGTCTGTACAACATCTTGAGTCCCTTTTTACCTCTATTACCAATTTTCTTTTG| |TCTTTGGGTATACATTTGAACCCTAATAAAACCAAACGTTGGGGCTACTCCCTTAACTTCATGGGATATGTAATTGGAAGTTGGGGTACTTTACCACAGG
Host Sequence
Chromosome
chrX
Cytoband
q26.2
Reference genome
GRCh37/hg19
Start
130843837/131709809 (Hg38)
End
130843837/131709809 (Hg38)
Orient
-
Location type
Intron
Target gene
FIRRE
Nearest miRNA
hsa-let-7f-2/Upstream/10338756; hsa-mir-105-1/Downstream/2459569;
Nearest TSS
ENST00000429181/Upstream/130910; ENST00000496850/Downstream/45857;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/626881, chrX-CpG: 26/Downstream/86096
Junction sequence
G
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).
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