Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10006057
Fusion event
HBV-USP9Y integration
Validated
No
Detection method
PCR and Ultra-deep sequencing
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
1792
Orient
+
Integrated sequence
ACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAGGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAA| |ATTGGTCTGTTCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGC
Host Sequence
Chromosome
chrY
Cytoband
q11.221
Reference genome
Start
End
14927990/12816055 (Hg38)
Orient
+
Location type
Intron
Target gene
Nearest miRNA
hsa-mir-3690-2/Upstream/8209827; hsa-mir-12120/Downstream/663122;
Nearest CpG islands
None/Target, chrY-CpG: 62/Upstream/278321, chrY-CpG: 52/Downstream/88578
Upstream sequence
catgaatggaaaagattggaaggaatggaatggaatggaatggaatggaatggaatggaatggaatggaatggaatggaatggagtggagtggagtggag
Downstream sequence
TTAGCCTGAAAATGGTGAACAGAATCACTGTTTTCATAGTATAAGCATCTTTTCTCTTTTCAACTCAGCTTGTGAAGCACTTACTGAGTGGGAATATCTG
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).