VISDB Viral Integration Site DataBase

VIS ID

TVIS10006069

Fusion event

HBV-NT5DC3 integration

Validated

No

Detection method

PCR and Ultra-deep sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Start

1790

Orient

+

Integrated sequence

CGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAGGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCAT| |AAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTG

Chromosome

chr12

Cytoband

q23.3

Reference genome

Start

End

104191905/103798127 (Hg38)

Orient

-

Location type

Intron

Target gene

miRNAs that regulate target gene

hsa-mir-193b-3p ; hsa-mir-335-5p ; hsa-mir-378a-5p ; hsa-mir-10a-5p ; hsa-mir-92a-3p ; hsa-mir-6516-5p ; hsa-mir-550b-2-5p ; hsa-mir-455-3p ; hsa-mir-1227-3p ; hsa-mir-650 ; hsa-mir-4252 ; hsa-mir-3612 ; hsa-mir-6499-3p ; hsa-mir-2467-3p ; hsa-mir-6086 ; hsa-mir-377-5p ; hsa-mir-1827 ; hsa-mir-4487 ; hsa-mir-558 ; hsa-mir-5186 ; hsa-mir-3160-3p ; hsa-mir-1247-3p ; hsa-mir-4257 ; hsa-mir-6511a-5p ; hsa-mir-1910-3p ; hsa-mir-4684-5p ; hsa-mir-8067 ; hsa-mir-6508-5p ; hsa-mir-3675-3p ; hsa-mir-5680 ; hsa-mir-28-3p ; hsa-mir-6771-3p ; hsa-mir-8060 ; hsa-mir-6894-3p ; hsa-mir-4763-5p ; hsa-mir-548s ; hsa-mir-6864-3p ; hsa-mir-3672 ; hsa-mir-3926 ; hsa-mir-769-5p ; hsa-mir-4786-5p ; hsa-mir-3190-5p ; hsa-mir-6849-3p ; hsa-mir-5582-3p ; hsa-mir-548f-3p ; hsa-mir-548e-3p ; hsa-mir-548az-3p ; hsa-mir-548ar-3p ; hsa-mir-548a-3p ; hsa-mir-6801-3p ; hsa-mir-2681-5p ; hsa-mir-4752 ; hsa-mir-6833-5p ; hsa-mir-7847-3p ; hsa-mir-505-5p ; hsa-mir-4289 ; hsa-mir-503-5p ; hsa-mir-6512-5p ; hsa-mir-34a-3p ; hsa-mir-6827-3p ; hsa-mir-340-3p ; hsa-mir-3613-3p ; hsa-mir-548c-3p ; hsa-mir-1273e ; hsa-mir-25-5p ; hsa-mir-34b-3p ; hsa-mir-3614-5p ; hsa-mir-3929 ; hsa-mir-4419b ; hsa-mir-4459 ; hsa-mir-4478 ; hsa-mir-4649-3p ; hsa-mir-4695-5p ; hsa-mir-4722-5p ; hsa-mir-4768-3p ; hsa-mir-485-5p ; hsa-mir-5690 ; hsa-mir-6087 ; hsa-mir-6500-3p ; hsa-mir-658 ; hsa-mir-665 ; hsa-mir-6746-5p ; hsa-mir-6771-5p ; hsa-mir-6884-5p ; hsa-mir-7160-5p

Nearest miRNA

hsa-let-7i/Upstream/3608178; hsa-mir-1178/Downstream/132298;

Nearest TSS

Nearest CpG islands

None/Target, chr12-CpG: 104/Upstream/302062, chr12-CpG: 87/Downstream/42368

Upstream sequence

tcaaaaaattctaagtagaatcattgtaagtcaggggctgtctgTACTAAGTTTACTAGCTGACCGAGCATCGTCCATTTCATTTTGACAAAGCAAGTAA

Downstream sequence

GTGAGTGCATCTAGTAAGACAAGAAGCAAAAATTCTGAGTGGAAAGAGAACCACAAAAGATAGAAAAGCAGAGGTTTCCCTGAAGGTAAAAAGGGTGGCT