Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10006077
Fusion event
HBV-HS1BP3 integration
Validated
No
Detection method
PCR and Ultra-deep sequencing
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
1789
Orient
+
Integrated sequence
CCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAGGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCA| |TAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGT
Host Sequence
Chromosome
chr2
Cytoband
p24.1
Reference genome
Start
End
20850746/20650986 (Hg38)
Orient
-
Location type
Intron
Target gene
miRNAs that regulate target gene
Nearest miRNA
hsa-mir-3125/Upstream/1302481; hsa-mir-10b/Downstream/4677654;
Nearest CpG islands
chr2-CpG: 56/Target, None/Upstream, None/Downstream
Upstream sequence
GGGCCCAGCCCGGATAAGCCACCGAGGGCGCTGGGGAGACCTGCACCAGGTCCCTGGCCTAGGAGGCGGCGGCCTCCCCCCGCCTCTCCGCCCGGGCGCC
Downstream sequence
CCGGACTGCGAGCTGTGCGGTGTGGGGCGCGGGGGTCTGGCTCACCTGGAGGTGACGAGCACCGCCGGGGACTGCATGACGGCGGCGGGGACTCCGGGCG
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).