Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10006097
Fusion event
HBV-USP9Y integration
Validated
No
Detection method
PCR and Ultra-deep sequencing
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
1789
Orient
+
Integrated sequence
CCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAGGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCA| |TAAATTGGTCTGTTCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGT
Host Sequence
Chromosome
chrY
Cytoband
q11.221
Reference genome
Start
End
14927993/12816058 (Hg38)
Orient
+
Location type
Intron
Target gene
Nearest miRNA
hsa-mir-3690-2/Upstream/8209830; hsa-mir-12120/Downstream/663119;
Nearest CpG islands
None/Target, chrY-CpG: 62/Upstream/278324, chrY-CpG: 52/Downstream/88575
Upstream sequence
gcattccattccgtttgattccagtccatccaagaaagttccattccagtccattgctttccagtccattccattccactctagtctattccactccatt
Downstream sequence
GCCTGAAAATGGTGAACAGAATCACTGTTTTCATAGTATAAGCATCTTTTCTCTTTTCAACTCAGCTTGTGAAGCACTTACTGAGTGGGAATATCTGCCC
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).