NAALADL2 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10006101
Fusion event
HBV-NAALADL2 integration
Validated
No
Detection method
PCR and Ultra-deep sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
29861854
Virus Sequence
Virus name
HBV
Reference genome
AP011098
Start
1222
Orient
-
Integrated sequence
TGTAAACAATATCTGCACCTTTACCCCGTTGCCCGGCAACGGTCAGGTCTCTGCCAAGTGTTTGCTGACGCAACCCCCACTGGATGGGGCTTGGCCATAG| |GCCATCGGCGCATGCGTGGAACCTTTGTGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCAGCTTGTTTTGCTCGCAGCCGGTCTGGAGCAAAACT
Host Sequence
Chromosome
chr3
Cytoband
q26.31
Reference genome
GRCh37/hg19
Start
174275642/174557852 (Hg38)
End
174275642/174557852 (Hg38)
Orient
-
Location type
Intronic
Target gene
NAALADL2
Nearest miRNA
hsa-let-7g/Upstream/3451093; hsa-mir-1224/Downstream/811688;
Nearest TSS
ENST00000440867/Upstream/116865; ENST00000485853/Downstream/301428;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/116294, chr3-CpG: 133/Downstream/2638597
Junction sequence
AATAGCC
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).
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