Fusion event
HBV-LOC105373779 integration
Detection method
PCR and Ultra-deep sequencing
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Integrated sequence
TTTAAGGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACT| |TTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTATAAA
End
185327603/184462876 (Hg38)
Nearest miRNA
hsa-mir-10b/Upstream/83832; hsa-mir-1244-1/Downstream/3834616;
Upstream sequence
AAGACATTTTCCATCACAAGGACACAAAAATAGAAACAGAATTATTATGAATTTATTTCAGGACATTAATGTATTTCCATCTTTCTTTGCATTTATAAAA
Downstream sequence
TGTCAAGTATTTTCAAATAGTTTGCCTACTATTAGGGATCTAATACGTATTTGTCTTGATATAGTGGATGAACGTCTATATTCTCTGTCTCTTCAATAGC
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).