Basic Information
VIS ID
TVIS10006136
Fusion event
HBV-LOC105373779 integration
Validated
No
Detection method
PCR and Ultra-deep sequencing
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
1821
Orient
+
Integrated sequence
TTTAAGGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAACT| |TTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTATAAA
Host Sequence
Chromosome
chr2
Cytoband
q32.1
Reference genome
End
185327603/184462876 (Hg38)
Orient
+
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-10b/Upstream/83832; hsa-mir-1244-1/Downstream/3834616;
Upstream sequence
AAGACATTTTCCATCACAAGGACACAAAAATAGAAACAGAATTATTATGAATTTATTTCAGGACATTAATGTATTTCCATCTTTCTTTGCATTTATAAAA
Downstream sequence
TGTCAAGTATTTTCAAATAGTTTGCCTACTATTAGGGATCTAATACGTATTTGTCTTGATATAGTGGATGAACGTCTATATTCTCTGTCTCTTCAATAGC
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).
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