IQGAP2 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10006150
Fusion event
HBV-IQGAP2 integration
Validated
No
Detection method
PCR and Ultra-deep sequencing
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
29861854
Virus Sequence
Virus name
HBV
Reference genome
AP011098
Start
1455
Orient
+
Integrated sequence
GAAATACACCTCCTTCCCATGGCTGCTCGGGTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGTCGGCGCTGAATCCCGCGGAC| |GACCCGTCTCGGGGCCGTTTGGGGCTCTACCGTCCCCTTCTTCATCTGCCGTTCCGGCCGACCACGGGGCGCACCTCTCTTTACGCGGTCTCCCCGTCTG
Host Sequence
Chromosome
chr5
Cytoband
q13.3
Reference genome
GRCh37/hg19
Start
75891192/76595367 (Hg38)
End
75891192/76595367 (Hg38)
Orient
-
Location type
Intron
Target gene
IQGAP2
miRNAs that regulate target gene
hsa-mir-499a-5p ; hsa-mir-208b-3p ; hsa-mir-208a-3p ; hsa-mir-549a ; hsa-mir-641 ; hsa-mir-3617-5p ; hsa-mir-548e-5p ; hsa-mir-92a-1-5p
Nearest miRNA
hsa-mir-10397/Upstream/3716704; hsa-mir-103a-1/Downstream/6244788;
Nearest TSS
ENST00000502646/Upstream/47958; ENST00000504815/Downstream/1707;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/191032, chr5-CpG: 111/Downstream/119928
Nearest cancer related gene
IQGAP2(TSG, No orient, 0)
Junction sequence
AAAAGCT
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).
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