Basic Information
VIS ID
TVIS10006160
Fusion event
HBV-chr8 integration
Validated
No
Detection method
PCR and Ultra-deep sequencing
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
1680
Orient
+
Integrated sequence
GCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCACCAGGTCTTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAA| |TGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAGGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGG
Host Sequence
Chromosome
chr8
Cytoband
q24.22
Reference genome
End
135835512/134823269 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-1204/Upstream/18324; hsa-mir-10400/Downstream/5909295;
Nearby gene
LOC102723694(-9766) ;
Upstream sequence
GGCAATGGTAGGAAGCATCAGTAGAAATGTTATTCATTAAAGACAGTTCAAATAAAAATGAATGTTACTTTTAAGGAACTTATCTTTTACTAAGCATACT
Downstream sequence
GTAACTAACTAAAAATCTTAAGTTTAAAAAAAATTAGATACTCAAGTATTAAAGCAATTATCTTTAAAAGATGAAAATGATGCACAATAAATATTGATTT
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).
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