PASD1 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10006168
Fusion event
HBV-PASD1 integration
Validated
No
Detection method
PCR and Ultra-deep sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
29861854
Virus Sequence
Virus name
HBV
Reference genome
AP011098
Start
41
Orient
-
Integrated sequence
CTCCACAACATTCCACCAAGCTCTGCTAGATCCCAGAGTGA| |GGGGCCTATATTTTCCTGCTGGTGGCTCCAGTTCCGGAACAGTAAACCCTGTTCCGACTACTGCCTCACCCATATCGTCAATCTTCTCGAGGACTGGGGA
Host Sequence
Chromosome
chrX
Cytoband
q28
Reference genome
GRCh37/hg19
Start
150837860/151669388 (Hg38)
End
150837860/151669388 (Hg38)
Orient
-
Location type
Intron
Fragile sites / regions
FRAXE ; FRAXF
Target gene
PASD1
Nearest miRNA
hsa-let-7f-2/Upstream/501062; hsa-mir-105-1/Downstream/289190;
Nearest TSS
ENST00000429181/Upstream/105659; ENST00000448726/Downstream/25736;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/271995, chrX-CpG: 98/Downstream/25319
Upstream sequence
aggattccctatttaataaatggtgctgggaaaactggctagccatatgtagaaaactgaaactggatcccttccttacaccttatacaaaaatcaattc
Downstream sequence
ttttttctttgtgttgggagcattacaattcttttagctattttaaaatatacaatagattgttttaactctaattttcctacttgagtactagaacttg
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).
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