VISDB Viral Integration Site DataBase

VIS ID

TVIS10006177

Fusion event

HBV-CRISPLD2 integration

Validated

No

Detection method

PCR and Ultra-deep sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2018

PubMed ID

Virus name

HBV

Reference genome

Start

1820

Orient

-

Integrated sequence

GTTTAAGGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGTTCACCAGCACCATGCAAC| |TTTTTCACCTCTGCCTAATCATCTCATGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTATAA

Chromosome

chr16

Cytoband

q24.1

Reference genome

Start

End

84906460/84872854 (Hg38)

Orient

-

Location type

Intron

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-1273e ; hsa-mir-6807-5p ; hsa-mir-6778-5p ; hsa-mir-1233-5p ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-650 ; hsa-mir-3612 ; hsa-mir-6894-5p ; hsa-mir-7160-5p ; hsa-mir-661 ; hsa-mir-2467-3p ; hsa-mir-6134 ; hsa-mir-6884-5p ; hsa-mir-7854-3p ; hsa-mir-485-5p ; hsa-mir-6823-3p ; hsa-mir-1827 ; hsa-mir-2114-3p ; hsa-mir-3192-5p ; hsa-mir-7162-3p ; hsa-mir-665 ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929 ; hsa-mir-6511a-5p ; hsa-mir-1910-3p ; hsa-mir-4695-5p ; hsa-mir-5089-5p ; hsa-mir-5589-5p ; hsa-mir-6506-5p ; hsa-mir-4731-5p ; hsa-mir-619-5p ; hsa-mir-6504-3p ; hsa-mir-512-3p ; hsa-mir-3120-3p ; hsa-mir-520e ; hsa-mir-520d-3p ; hsa-mir-520c-3p ; hsa-mir-520b ; hsa-mir-520a-3p ; hsa-mir-373-3p ; hsa-mir-372-3p ; hsa-mir-302e ; hsa-mir-302d-3p ; hsa-mir-302c-3p ; hsa-mir-302b-3p ; hsa-mir-302a-3p ; hsa-mir-93-5p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-106a-5p ; hsa-mir-4252 ; hsa-mir-1273g-3p ; hsa-mir-6848-3p ; hsa-mir-6843-3p ; hsa-mir-6131 ; hsa-mir-6821-3p ; hsa-mir-6790-3p ; hsa-mir-3663-5p ; hsa-mir-6078 ; hsa-mir-614 ; hsa-mir-8485 ; hsa-mir-4643 ; hsa-mir-6768-5p ; hsa-mir-8057 ; hsa-mir-6836-3p ; hsa-mir-5001-3p ; hsa-mir-24-3p ; hsa-mir-3194-3p ; hsa-mir-6829-3p ; hsa-mir-6791-3p ; hsa-mir-6778-3p ; hsa-mir-2276-3p ; hsa-mir-4532 ; hsa-mir-1247-3p ; hsa-mir-6890-3p ; hsa-mir-6796-3p ; hsa-mir-197-3p ; hsa-mir-143-5p ; hsa-mir-4430 ; hsa-mir-3652 ; hsa-mir-4284 ; hsa-mir-4634 ; hsa-mir-504-3p ; hsa-mir-3135b ; hsa-mir-6499-3p ; hsa-mir-4638-5p ; hsa-mir-1307-3p ; hsa-mir-6511b-3p ; hsa-mir-6511a-3p ; hsa-mir-6741-3p ; hsa-mir-5693 ; hsa-mir-4659b-3p ; hsa-mir-4659a-3p ; hsa-mir-4303 ; hsa-mir-22-5p ; hsa-mir-4668-5p ; hsa-mir-6081 ; hsa-mir-3182 ; hsa-mir-6761-5p ; hsa-mir-4329 ; hsa-mir-4251 ; hsa-mir-3613-3p ; hsa-mir-548p ; hsa-mir-148a-5p ; hsa-mir-765 ; hsa-mir-7154-3p ; hsa-mir-766-5p ; hsa-mir-4717-3p ; hsa-mir-4802-5p ; hsa-mir-4802-3p ; hsa-mir-574-5p ; hsa-mir-6867-5p ; hsa-mir-4711-3p ; hsa-mir-6812-3p ; hsa-mir-8064 ; hsa-mir-4768-3p ; hsa-mir-5584-3p ; hsa-mir-215-3p ; hsa-mir-6773-3p ; hsa-mir-651-5p ; hsa-mir-4266 ; hsa-mir-7977 ; hsa-mir-383-3p ; hsa-mir-708-5p ; hsa-mir-3139 ; hsa-mir-28-5p ; hsa-mir-524-5p ; hsa-mir-520d-5p ; hsa-mir-7853-5p ; hsa-mir-105-5p ; hsa-mir-4707-3p ; hsa-mir-150-5p ; hsa-mir-7107-5p ; hsa-mir-1234-3p ; hsa-mir-186-3p ; hsa-mir-520h ; hsa-mir-520g-3p ; hsa-mir-2355-3p ; hsa-mir-676-3p ; hsa-mir-6727-3p ; hsa-mir-4722-3p ; hsa-mir-1203 ; hsa-mir-7111-3p ; hsa-mir-642a-5p ; hsa-mir-6515-3p ; hsa-mir-381-3p ; hsa-mir-300 ; hsa-mir-6867-3p

Nearest miRNA

hsa-mir-1225/Upstream/1364446; hsa-mir-11401/Downstream/334942;

Nearest TSS

Nearest CpG islands

None/Target, chr16-CpG: 29/Upstream/52746, chr16-CpG: 67/Downstream/138270

Junction sequence