Basic Information
VIS ID
TVIS10006185
Fusion event
HBV-LOC102724104 integration
Validated
No
Detection method
PCR and Ultra-deep sequencing
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
29861854
Virus Sequence
Virus name
HBV
Reference genome
AP011098
Start
1024
Orient
-
Integrated sequence
GTACGGAAACTCAAGCAATGTTTTCGAAAACTGCCTGTAAATAGACCTATTGATTGGAAAGTATGTCAAAGAATTGTGGGTCTTTTGGGCTTTGCTGCCC| |CTTTTACACAATGTGGCTATCCTGCCTTGATGCCTTTATATGCATGTATACAATCTAAGCAGGCTTTCACTTTCTCGCCAACTTACAAGGCCTTTCTGTG
Host Sequence
Chromosome
chr3
Cytoband
p22.2
Reference genome
GRCh37/hg19
Start
39292666/39251175 (Hg38)
End
39292666/39251175 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC102724104
Nearest miRNA
hsa-mir-12127/Upstream/112909; hsa-let-7g/Downstream/4863037;
Nearest TSS
ENST00000440867/Upstream/58579; ENST00000326306/Downstream/28859;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/69996, chr3-CpG: 125/Downstream/132030
Upstream sequence
TTATCGTTATTAGTGTTTTCATAATATTAGTGATAAGTTTTTCAATTCTGTACATATGCCGACTATCCCCTCACTTGGATTGTACATTACATTTTCAAGT
Downstream sequence
GCCTTGCCAAAActttccttccatctcttccacacagggaacagacctgtgttgtggtctggaggcttctcagcctctcacagcctccctttttccctca
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).
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