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VISDB
Viral Integration Site DataBase
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TVIS10006220
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10006220
Fusion event
HBV-REXO1 integration
Validated
No
Detection method
PCR and Ultra-deep sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
29861854
Virus Sequence
Virus name
HBV
Reference genome
AP011098
Start
1456
Orient
+
Integrated sequence
AAATACACCTCCTTCCCATGGCTGCTCGGGTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGTCGGCGCTGAATCCCGCGGACG| |ACCCGTCTCGGGGCCGTTTGGGGCTCTACCGTCCCCTTCTTCATCTGCCGTTCCGGCCGACCACGGGGCGCACCTCTCTTTACGCGGTCTCCCCGTCTGT
Host Sequence
Chromosome
chr19
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
1840659/1840660 (Hg38)
End
1840659/1840660 (Hg38)
Orient
-
Location type
Intron
Fragile sites / regions
FRA19B
Target gene
REXO1
miRNAs that regulate target gene
hsa-mir-484
;
hsa-mir-30d-5p
;
hsa-mir-30a-5p
;
hsa-mir-6810-5p
;
hsa-mir-491-5p
;
hsa-mir-92a-2-5p
;
hsa-mir-675-5p
;
hsa-mir-4466
;
hsa-mir-6766-5p
;
hsa-mir-6756-5p
;
hsa-mir-4664-5p
;
hsa-mir-4652-5p
;
hsa-mir-342-5p
;
hsa-mir-3191-3p
;
hsa-mir-3144-5p
;
hsa-mir-25-5p
;
hsa-mir-6820-5p
;
hsa-mir-658
;
hsa-mir-6738-5p
;
hsa-mir-5194
;
hsa-mir-1914-3p
;
hsa-mir-6782-5p
;
hsa-mir-6858-5p
;
hsa-mir-4689
;
hsa-mir-6081
;
hsa-mir-4707-3p
;
hsa-mir-2467-3p
;
hsa-mir-4784
;
hsa-mir-3150b-3p
;
hsa-mir-7114-3p
;
hsa-mir-4468
;
hsa-mir-1180-5p
;
hsa-mir-551b-3p
;
hsa-mir-551a
;
hsa-mir-7108-3p
;
hsa-mir-662
;
hsa-mir-32-5p
;
hsa-mir-92b-3p
;
hsa-mir-195-5p
;
hsa-mir-92a-3p
;
hsa-mir-16-5p
;
hsa-mir-15b-5p
;
hsa-mir-15a-5p
;
hsa-mir-1203
;
hsa-mir-1251-5p
;
hsa-mir-1301-5p
;
hsa-mir-1909-3p
;
hsa-mir-3151-5p
;
hsa-mir-3165
;
hsa-mir-3180-3p
;
hsa-mir-3180
;
hsa-mir-3190-3p
;
hsa-mir-3196
;
hsa-mir-328-5p
;
hsa-mir-3656
;
hsa-mir-4283
;
hsa-mir-4285
;
hsa-mir-4446-3p
;
hsa-mir-4467
;
hsa-mir-4492
;
hsa-mir-4498
;
hsa-mir-4505
;
hsa-mir-4508
;
hsa-mir-4651
;
hsa-mir-4669
;
hsa-mir-4721
;
hsa-mir-4722-5p
;
hsa-mir-4731-5p
;
hsa-mir-4768-3p
;
hsa-mir-4781-5p
;
hsa-mir-486-3p
;
hsa-mir-5001-5p
;
hsa-mir-504-3p
;
hsa-mir-5787
;
hsa-mir-6079
;
hsa-mir-6087
;
hsa-mir-608
;
hsa-mir-6132
;
hsa-mir-637
;
hsa-mir-6502-5p
;
hsa-mir-671-5p
;
hsa-mir-6722-3p
;
hsa-mir-6733-3p
;
hsa-mir-6795-5p
;
hsa-mir-6804-5p
;
hsa-mir-6816-3p
;
hsa-mir-6816-5p
;
hsa-mir-6822-3p
;
hsa-mir-6828-5p
;
hsa-mir-6836-5p
;
hsa-mir-6847-5p
;
hsa-mir-6880-5p
;
hsa-mir-6885-5p
;
hsa-mir-6887-5p
;
hsa-mir-7109-5p
;
hsa-mir-7154-3p
;
hsa-mir-7-5p
;
hsa-mir-762
;
hsa-mir-8071
;
hsa-mir-92b-5p
Nearest miRNA
hsa-mir-1302-11/Upstream/24422; hsa-let-7e/Downstream/393402;
Nearest TSS
ENST00000633603/Upstream/18616;
ENST00000592884/Downstream/7786;
Nearest CpG islands
None/Target,
chr19-CpG: 112/Upstream/12113
,
chr19-CpG: 20/Downstream/7030
Upstream sequence
CTTCCAGCCACAGGCAAACTCCTATTCATCCTCCAAAACCCAGCCCAGTAATCCTGTGTTTGGAAACACTCGCCCCACCCCCCTGCAACTCTGAGTGACA
Downstream sequence
CCCGGGCCCGCCCCACGTCACCCCTCCACTCCCTGCAACTCCAAGTGACAGCTGCCCTGTCTCCTGGACCCGGGCCCACCCCACATCACCCCCTCCGCTT
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).
Sample Information
×
Sample name
RK275_T
Sample type
Tumor
Sample size
25mm
Age
48
Gender
Female
CpG Island Information
×
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