Basic Information
VIS ID
TVIS10006224
Fusion event
HBV-chr20 integration
Validated
No
Detection method
PCR and Ultra-deep sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
29861854
Virus Sequence
Virus name
HBV
Reference genome
AP011098
Start
1084
Orient
-
Integrated sequence
GTATGTCAAAGAATTGTGGGTCTTTTGGGCTTTGCTGCCCCTTTTACACAATGTGGCTATCCTGCCTTGATGCCTTTATATGCATGTATACAATCTAAGC| |AGGCTTTCACTTTCTCGCCAACTTACAAGGCCTTTCTGTGTAAACAATATCTGCACCTTTACCCCGTTGCCCGGCAACGGTCAGGTCTCTGCCAAGTGTT
Host Sequence
Chromosome
chr20
Cytoband
q13.33
Reference genome
GRCh37/hg19
Start
62918282/64286929 (Hg38)
End
62918282/64286929 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-1-1/Upstream/209919;
Nearest TSS
ENST00000382410/Upstream/15447; ENST00000279067/Downstream/3456;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/16368, chr20-CpG: 92/Downstream/29366
Nearby gene
CICP4(+3456) ;
Junction sequence
TAAA
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).
Curate