Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10006239
Fusion event
HBV-ACSM2A integration
Validated
No
Detection method
PCR and Ultra-deep sequencing
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
1478
Orient
+
Integrated sequence
TGCTCGGGTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTCTACGTCCCGTCGGCGCTGAATCCCGCGGACGACCCGTCTCGGGGCCGTTTGGG| |GCTCTACCGTCCCCTTCTTCATCTGCCGTTCCGGCCGACCACGGGGCGCACCTCTCTTTACGCGGTCTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGT
Host Sequence
Chromosome
chr16
Cytoband
p12.3
Reference genome
Start
End
20494890/20483568 (Hg38)
Orient
+
Location type
Intron
Target gene
miRNAs that regulate target gene
hsa-mir-18a-3p ; hsa-mir-3184-3p ; hsa-mir-6818-3p ; hsa-mir-6888-3p ; hsa-mir-6873-3p ; hsa-mir-593-3p ; hsa-mir-6895-3p ; hsa-mir-3120-5p ; hsa-mir-6817-3p ; hsa-mir-7110-3p ; hsa-mir-3615 ; hsa-mir-6812-3p ; hsa-mir-216b-5p ; hsa-mir-6807-5p ; hsa-mir-8055 ; hsa-mir-6844 ; hsa-mir-3191-5p ; hsa-mir-6758-3p ; hsa-mir-5571-5p ; hsa-mir-4742-3p ; hsa-let-7a-2-3p ; hsa-let-7g-3p ; hsa-mir-218-2-3p ; hsa-mir-374a-5p ; hsa-mir-374b-5p ; hsa-mir-4320 ; hsa-mir-4797-5p ; hsa-mir-526b-5p ; hsa-mir-6847-5p
Nearest miRNA
hsa-mir-1225/Upstream/1988992; hsa-mir-11401/Downstream/1022481;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/134392, chr16-CpG: 65/Downstream/257756
Junction sequence
AGCGG
* Color:
Human Sequence
/
Virus Sequence
/
Overlapped sequence
/
Unknown sequence
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).