Fusion event
HBV-C7orf50 integration
Detection method
PCR and Ultra-deep sequencing
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Integrated sequence
TCTGCCGTTCCGGCCGACCACGGGGCGCACCTCTCTTTACGCGGTCTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTG| |CACGTCGCATGGAGACCACCGTGAACGCCCACCAGGTCTTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGA
End
1062386/1022750 (Hg38)
Nearest miRNA
hsa-mir-10399/Downstream/183;
Upstream sequence
AATGGGAAATTAAGAGTGTTATTCTGACCTCTAGGGTAGAGAATGGGACCTCTGCTCAGCTTTAAGTGAGGAGCAAGACAGAATAGTGATGGTGAGCCCT
Downstream sequence
CAACCGTCCTCCCTCCCCAGTTACTTCCTCCCTAGGACACCAGTGGAACATCCCATGCTCTCCCCCTTCCATGTTGATACCGAATAAAACACACTGCATC
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).