Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10006260
Fusion event
HBV-C7orf50 integration
Validated
No
Detection method
PCR and Ultra-deep sequencing
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2018
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
1933
Orient
-
Integrated sequence
CCTAATCATCTCATGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATTGACCCGTATAAAGAATTTGGAGCT| |TCTGTGGAGTTACTCTCTTTTTTGCCTTCTGACTTCTTTCCTTCTATTCGAGATCTCCTCGACACCGCCTCTGCTCTGTATCGGGAGGCCTTAGAGTCTC
Host Sequence
Chromosome
chr7
Cytoband
p22.3
Reference genome
Start
End
1062364/1022728 (Hg38)
Orient
+
Location type
Intron
Fragile sites / regions
Target gene
Nearest miRNA
hsa-mir-10399/Downstream/205;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/2487, chr7-CpG: 40/Downstream/132
Upstream sequence
GGCACGGTGTGGGTGTGACTTGCTATGACTTTTTAACAGCTGACTCCACCTGCGGGCAAGTCCACTTCATTTCCACCTCAGCAAATGCGGTGATTAACTG
Downstream sequence
TTCTTTAAAGGTGAATCCCCCCCAACCGTCCTCCCTCCCCAGTTACTTCCTCCCTAGGACACCAGTGGAACATCCCATGCTCTCCCCCTTCCATGTTGAT
Reference
Tu, T., et al. Hepatitis B Virus DNA Integration Occurs Early in the Viral Life Cycle in an In Vitro Infection Model via Sodium Taurocholate Cotransporting Polypeptide-Dependent Uptake of Enveloped Virus Particles. J Virol ,2018,92(11).