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VISDB
Viral Integration Site DataBase
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TVIS10006322
Basic Information
VIS ID
TVIS10006322
Fusion event
HBV-chr2 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
1805
Integrated sequence
TCCCAAGCGACCCCGAGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGC| |AGCCATGGAAACGATGTATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCTAGGA
Host Sequence
Chromosome
chr2
Cytoband
q32.1
Reference genome
GRCh38
Start
187112119 (Hg38)
End
187112119 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-10b/Upstream/2733075; hsa-mir-1244-1/Downstream/1185373;
Nearest TSS
ENST00000437798/Upstream/108845;
ENST00000428329/Downstream/336027;
Nearest CpG islands
None/Target,
chr2-CpG: 135/Upstream/262777
,
chr2-CpG: 106/Downstream/1179570
Nearby gene
ZSWIM2
(-262949) ;
CALCRL
(+229843) ;
Upstream sequence
GCAGTTATGTATATGTTTCT
Junction sequence
GCAGTTATGTATATGTTTCTCGCAGACCAATTTATGCCTA
* Color:
Human Sequence
/
Virus Sequence
/
Overlapped sequence
/
Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Sample Information
×
Sample name
1
Sample type
Tumor
Age
15
Gender
Female
CpG Island Information
×
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