Basic Information
VIS ID
TVIS10006323
Fusion event
HBV-chr7 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
1819
Integrated sequence
GAGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAGCCATGGAAACGA| |TGTATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCTAGGAGTTCCGCAGTATGG
Host Sequence
Chromosome
chr7
Cytoband
q36.3
Reference genome
GRCh38
Start
156990872 (Hg38)
End
156990872 (Hg38)
Location type
Intergenic
Fragile sites / regions
FRA7I
Nearest miRNA
hsa-mir-10399/Upstream/5557233; hsa-mir-153-2/Downstream/583464;
Nearest TSS
ENST00000635602/Upstream/22117; ENST00000429228/Downstream/15435;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/22330, chr7-CpG: 100/Downstream/8752
Nearby gene
NOM1(-17690) ; MNX1(+13980) ;
Downstream sequence
GACTGTGTCTATCATTGGG
Junction sequence
TCTGCGCACCAGCACCATGCTCGACTGTGTCTATCATTGGG
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Curate