VISDB Viral Integration Site DataBase

VIS ID

TVIS10006330

Fusion event

HBV-PPP1R37 integration

Validated

Yes

Detection method

invPCR +Sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Perfect

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1735

Integrated sequence

GGGAGTCCGCGTAAAGAGAGGTGCGCCCCGTGGTCGGTCGGAACGGCAGACGGAGAAGGGGACGAGAGAGTCCCAAGCGACCCCGAGAAGGGTCGTCCGC| |AGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAGCCATGGAAACGATGTATATTTGCGGGAT

Chromosome

chr19

Cytoband

q13.32

Reference genome

Start

End

45113949 (Hg38)

Location type

Intron

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-25-3p ; hsa-mir-32-5p ; hsa-mir-92a-3p ; hsa-mir-125b-5p ; hsa-mir-125a-5p ; hsa-mir-363-3p ; hsa-mir-367-3p ; hsa-mir-345-3p ; hsa-mir-92b-3p ; hsa-mir-670-5p ; hsa-mir-4319 ; hsa-mir-4325 ; hsa-mir-4732-3p ; hsa-mir-6736-3p ; hsa-mir-7106-3p ; hsa-mir-7113-3p ; hsa-mir-7703 ; hsa-mir-4323 ; hsa-mir-4797-5p ; hsa-mir-6796-3p ; hsa-mir-4267 ; hsa-mir-500a-3p ; hsa-mir-580-3p ; hsa-mir-539-5p ; hsa-mir-137

Nearest miRNA

hsa-mir-10395/Upstream/355228; hsa-let-7e/Downstream/322705;

Nearest TSS

Nearest CpG islands

None/Target, chr19-CpG: 112/Upstream/20336, chr19-CpG: 73/Downstream/30750

Downstream sequence

TGGCTCTGCTTGCTCTTT

Junction sequence