PI4KA _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10006333
Fusion event
HBV-PI4KA integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
1807
Integrated sequence
CCAAGCGACCCCGAGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAG| |CCATGGAAACGATGTATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCTAGGAGT
Host Sequence
Chromosome
chr22
Cytoband
q11.21
Reference genome
GRCh38
Start
20814502 (Hg38)
End
20814502 (Hg38)
Location type
Intron
Target gene
PI4KA
miRNAs that regulate target gene
hsa-mir-484 ; hsa-mir-93-5p ; hsa-mir-218-5p
Nearest miRNA
hsa-mir-1286/Upstream/565291; hsa-let-7a-3/Downstream/219674;
Nearest TSS
ENST00000624155/Upstream/12484; ENST00000490458/Downstream/44310;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/109997, chr22-CpG: 106/Downstream/43920
Downstream sequence
AGTTTTCGAAGGCTGAGG
Junction sequence
GGCATAAATTGGTCTGCGCAAGTTTTCGAAGGCTGAGG
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Curate