VISDB Viral Integration Site DataBase

VIS ID

TVIS10006334

Fusion event

HBV-TNFRSF1B integration

Validated

Yes

Detection method

invPCR +Sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Perfect

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1906

Integrated sequence

GCCATGGAAACGATGTATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCTAGGAG| |TTCCGCAGTATGGATCGGCAGAGGAGCCGAAAAGGTTCCACGCATGCGCTGATGGCCCATGACCAAGCCCCAGCCAGTGGGGGTTGCGTCAGCAAACACT

Chromosome

chr1

Cytoband

p36.22

Reference genome

Start

End

12184317 (Hg38)

Location type

Intron

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-193a-3p ; hsa-mir-193b-3p ; hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-6852-3p ; hsa-mir-3909 ; hsa-mir-6891-3p ; hsa-mir-6072 ; hsa-mir-6884-3p ; hsa-mir-3607-5p ; hsa-mir-299-3p ; hsa-mir-96-3p

Nearest miRNA

hsa-mir-12136/Upstream/17279; hsa-mir-101-1/Downstream/7396;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/16662, chr1-CpG: 51/Downstream/6960

Nearest cancer related gene

TNFRSF1B(OG, No orient, 0)

Downstream sequence

TCATTGTTTAGCCATGAC

Junction sequence