VISDB Viral Integration Site DataBase

VIS ID

TVIS10006335

Fusion event

HBV-TBC1D14 integration

Validated

Yes

Detection method

invPCR +Sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Perfect

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1825

Integrated sequence

GGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAGCCATGGAAACGATGTATA| |TTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCTAGGAGTTCCGCAGTATGGATCGGC

Chromosome

chr4

Cytoband

p16.1

Reference genome

Start

End

6942259 (Hg38)

Location type

Intron

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-155-5p ; hsa-mir-320a ; hsa-mir-16-5p ; hsa-mir-195-5p ; hsa-mir-15b-5p ; hsa-mir-15a-5p ; hsa-mir-149-5p ; hsa-mir-24-3p ; hsa-mir-4252 ; hsa-mir-4268 ; hsa-mir-4284 ; hsa-mir-4448 ; hsa-mir-6772-3p ; hsa-mir-892b

Nearest miRNA

hsa-mir-378d-1/Upstream/1018931; hsa-mir-12113/Downstream/368191;

Nearest TSS

Nearest CpG islands

None/Target, chr4-CpG: 46/Upstream/18395, chr4-CpG: 94/Downstream/44319

Upstream sequence

ACTGAATTATTTCATGCCTTC

Junction sequence