Basic Information
VIS ID
TVIS10006340
Fusion event
HBV-chr2 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
1871
Integrated sequence
CCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAGCCATGGAAACGATGTATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCT| |CCAGACCTGCTGCGAGCAAAACAAGCGGCTAGGAGTTCCGCAGTATGGATCGGCAGAGGAGCCGAAAAGGTTCCACGCATGCGCTGATGGCCCATGACCA
Host Sequence
Chromosome
chr2
Cytoband
q24.3
Reference genome
GRCh38
Start
164157155 (Hg38)
End
164157155 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-128-1/Upstream/3749273; hsa-mir-10b/Downstream/4425788;
Nearest TSS
ENST00000437798/Upstream/421143; ENST00000628960/Downstream/195068;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/420154, chr2-CpG: 87/Downstream/463897
Nearby gene
FIGN(-421152) ; GRB14(+335250) ;
Downstream sequence
AACTATGATAGTGGTGA
Junction sequence
TCATGTCCTACTGTTCAAGCAACTATGATAGTGGTGA
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Curate