Basic Information
VIS ID
TVIS10006343
Fusion event
HBV-chr1 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
1669
Integrated sequence
GTCTCCATGCGACGTGCAGAGGTGAAGCGAAGTGCACACGGTCCGGCAGATGAGAAGGCACAGACGGGGAGTCCGCGTAAAGAGAGGTGCGCCCCGTGGT| |CGGTCGGAACGGCAGACGGAGAAGGGGACGAGAGAGTCCCAAGCGACCCCGAGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGAC
Host Sequence
Chromosome
chr1
Cytoband
p21.2
Reference genome
End
100312508 (Hg38)
Location type
Intergenic
Fragile sites / regions
Nearest miRNA
hsa-mir-101-1/Upstream/31200; hsa-mir-11399/Downstream/7584715;
Nearby gene
RTCA(-19739) ; CDC14A(+39958) ;
Upstream sequence
AGTCATTTCTGTGTGATGGCT
Junction sequence
AGTCATTTCTGTGTGATGGCTTAAAATTAAGAGTCCTCTTA
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Curate