Basic Information
VIS ID
TVIS10006345
Fusion event
HBV-DIAPH2-AS1 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Host Sequence
Chromosome
chrX
Cytoband
q21.33
Reference genome
GRCh38
Start
97542265 (Hg38)
End
97542265 (Hg38)
Location type
Intron
Target gene
DIAPH2-AS1
Nearest miRNA
hsa-let-7f-2/Upstream/2479039; hsa-mir-105-1/Downstream/9097549;
Nearest TSS
ENST00000429181/Upstream/658357; ENST00000627700/Downstream/22240;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/856898, chrX-CpG: 23/Downstream/2397071
Upstream sequence
AGTCAGAAAGTCTTCnnn
Junction sequence
AGTCAGAAAGTCTTCnnnnnnnnnnnnnnnnnnnnnnnn
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Curate