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VISDB
Viral Integration Site DataBase
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TVIS10006356
Proximate region of VIS (GRCh38)
VIS
Enhancer
Enhancer/Promoter
Promoter
Gene
28256736
27950966
28177446
28083899
28088892
28062495
28067021
28090265
28091966
28098308
28099671
28074876
28076201
28073663
28074586
28079604
28080354
28094487
28094809
28078937
28079086
28103851
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10006356
Fusion event
HBV-CDH2 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
1920
Integrated sequence
GTATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCTAGGAGTTCCGCAGTATGGA| |TCGGCAGAGGAGCCGAAAAGGTTCCACGCATGCGCTGATGGCCCATGACCAAGCCCCAGCCAGTGGGGGTTGCGTCAGCAAACACTTGGCACAGACCTGG
Host Sequence
Chromosome
chr18
Cytoband
q12.1
Reference genome
GRCh38
Start
28103851 (Hg38)
End
28103851 (Hg38)
Location type
Intron
Target gene
CDH2
miRNAs that regulate target gene
hsa-mir-204-5p
;
hsa-mir-194-5p
;
hsa-mir-145-5p
;
hsa-mir-155-5p
;
hsa-mir-138-5p
;
hsa-mir-124-3p
;
hsa-mir-1-3p
;
hsa-mir-30a-5p
;
hsa-mir-27b-5p
;
hsa-mir-615-3p
;
hsa-mir-218-5p
;
hsa-mir-199a-5p
;
hsa-mir-412-3p
;
hsa-mir-411-5p
;
hsa-mir-216b-3p
;
hsa-mir-1244
;
hsa-mir-603
;
hsa-mir-8485
;
hsa-mir-338-3p
;
hsa-mir-506-3p
;
hsa-mir-153-5p
;
hsa-mir-208a-5p
;
hsa-mir-208b-5p
;
hsa-mir-587
Nearest miRNA
hsa-mir-1-2/Upstream/1512316; hsa-mir-122/Downstream/2195059;
Nearest TSS
ENST00000575820/Upstream/6622;
ENST00000582726/Downstream/55446;
Nearest CpG islands
None/Target,
chr18-CpG: 67/Upstream/918308
,
chr18-CpG: 257/Downstream/71599
Upstream sequence
TACTTTTATATGGCTGCA
Junction sequence
T
A
C
T
T
T
T
A
T
A
T
G
G
C
T
G
C
A
A
T
A
C
G
G
G
T
C
A
A
T
G
T
C
C
A
T
G
C
* Color:
Human Sequence
/
Virus Sequence
/
Overlapped sequence
/
Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Sample Information
×
Sample name
2
Sample type
Tumor
Age
17
Gender
Female
CpG Island Information
×
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