VISDB Viral Integration Site DataBase

VIS ID

TVIS10006372

Fusion event

HBV-TMEM117 integration

Validated

Yes

Detection method

invPCR +Sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Perfect

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1810

Integrated sequence

AGCGACCCCGAGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAGCCA| |TGGAAACGATGTATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCTAGGAGTTCC

Chromosome

chr12

Cytoband

q12

Reference genome

Start

End

43966271 (Hg38)

Location type

Intron

Target gene

miRNAs that regulate target gene

hsa-mir-5010-3p ; hsa-mir-192-3p ; hsa-mir-365b-5p ; hsa-mir-8052 ; hsa-mir-365a-5p ; hsa-mir-3199 ; hsa-mir-95-5p ; hsa-mir-4477a ; hsa-mir-2116-5p ; hsa-mir-19b-3p ; hsa-mir-19a-3p ; hsa-mir-302a-5p ; hsa-mir-195-3p ; hsa-mir-16-2-3p ; hsa-mir-5584-3p ; hsa-mir-6874-3p ; hsa-mir-148b-5p ; hsa-mir-3168 ; hsa-mir-5571-5p ; hsa-mir-8066

Nearest miRNA

hsa-mir-1244-3/Upstream/1642412; hsa-let-7i/Downstream/3221541;

Nearest TSS

Nearest CpG islands

None/Target, chr12-CpG: 104/Upstream/129910, chr12-CpG: 86/Downstream/909776

Upstream sequence

AAGAAGGGGATAAGAG

Junction sequence