Basic Information
VIS ID
TVIS10006373
Fusion event
HBV-chr19 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
1825
Integrated sequence
GGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAGCCATGGAAACGATGTATA| |TTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCTAGGAGTTCCGCAGTATGGATCGGC
Host Sequence
Chromosome
chr19
Cytoband
q12
Reference genome
GRCh38
Start
31760568 (Hg38)
End
31760568 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-10395/Upstream/11361214; hsa-let-7e/Downstream/3362132;
Nearest TSS
ENST00000633603/Upstream/164848; ENST00000593056/Downstream/147716;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/403265, chr19-CpG: 27/Downstream/463910
Nearby gene
THEG5(-167018) ; LINC01533(+265293) ;
Downstream sequence
AGAAGTGGGCATTGGCAC
Junction sequence
CNCCANCACCNTGCAACTTTAGAAGTGGGCATTGGCAC
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Curate