Basic Information
VIS ID
TVIS10006381
Fusion event
HBV-chr9 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Host Sequence
Chromosome
chr9
Cytoband
q22.31
Reference genome
GRCh38
Start
92115984 (Hg38)
End
92115984 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-101-2/Upstream/479623; hsa-let-7a-1/Downstream/176474;
Nearest TSS
ENST00000422679/Upstream/600; ENST00000457003/Downstream/89372;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/484, chr9-CpG: 39/Downstream/25306
Nearby gene
SPTLC1(-510) ; LOC100128076(+16849) ;
Upstream sequence
ggtcaggctggtctcaaactcctgacctcaggtgatccgcctgcctcggcctcccaaagtgctgggattagaggcgtgagccaccgcgcctggccAATAC
Downstream sequence
GTTTACGTTTAGTAGCATAAGTAATCCAGCAATGCATTATCATTAAGAAATGCATAATTATACACAAAAATAGCCAACCCATATAGCACTTCCTGTTTTG
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Curate