VISDB Viral Integration Site DataBase

VIS ID

TVIS10006382

Fusion event

HBV-SH3GLB1 integration

Validated

Yes

Detection method

invPCR +Sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Perfect

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1752

Integrated sequence

GAGGTGCGCCCCGTGGTCGGTCGGAACGGCAGACGGAGAAGGGGACGAGAGAGTCCCAAGCGACCCCGAGAAGGGTCGTCCGCAGGATTCAGCGCCGACG| |GGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAGCCATGGAAACGATGTATATTTGCGGGATAGGACAACAGAGTTATC

Chromosome

chr1

Cytoband

p22.3

Reference genome

Start

End

86733852 (Hg38)

Location type

Intron

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-29c-3p ; hsa-mir-93-5p ; hsa-let-7b-5p ; hsa-mir-21-3p ; hsa-mir-29a-3p ; hsa-mir-29b-3p ; hsa-mir-561-3p ; hsa-mir-767-5p ; hsa-mir-3920 ; hsa-mir-3591-3p ; hsa-mir-5682 ; hsa-mir-3192-3p ; hsa-mir-17-5p ; hsa-mir-20a-5p ; hsa-mir-106a-5p ; hsa-mir-106b-5p ; hsa-mir-302a-3p ; hsa-mir-302b-3p ; hsa-mir-302c-3p ; hsa-mir-302d-3p ; hsa-mir-372-3p ; hsa-mir-373-3p ; hsa-mir-20b-5p ; hsa-mir-520e ; hsa-mir-520a-3p ; hsa-mir-526b-3p ; hsa-mir-520b ; hsa-mir-520c-3p ; hsa-mir-519d-3p ; hsa-mir-520d-3p ; hsa-mir-302e ; hsa-mir-3121-3p ; hsa-mir-16-2-3p ; hsa-mir-195-3p ; hsa-mir-34a-3p ; hsa-mir-4310 ; hsa-mir-3617-3p ; hsa-mir-7157-5p ; hsa-mir-526b-5p ; hsa-mir-4650-3p ; hsa-mir-4635 ; hsa-mir-493-3p ; hsa-mir-5584-3p ; hsa-mir-6831-5p ; hsa-mir-3927-3p ; hsa-mir-148a-5p ; hsa-mir-3646 ; hsa-mir-6882-5p ; hsa-mir-3942-3p ; hsa-mir-127-5p ; hsa-mir-3928-5p ; hsa-mir-6806-3p ; hsa-mir-4761-3p ; hsa-mir-205-3p ; hsa-mir-7843-5p ; hsa-mir-6879-5p ; hsa-mir-6735-5p ; hsa-mir-4632-5p ; hsa-mir-4436b-3p ; hsa-mir-4796-3p ; hsa-mir-548ah-5p ; hsa-mir-3609 ; hsa-mir-552-5p ; hsa-mir-4762-3p ; hsa-mir-302c-5p ; hsa-mir-585-5p ; hsa-mir-29a-5p ; hsa-mir-6871-3p ; hsa-mir-4659b-3p ; hsa-mir-4659a-3p ; hsa-mir-6875-3p ; hsa-mir-6814-5p ; hsa-mir-633 ; hsa-mir-6809-3p ; hsa-mir-7156-5p ; hsa-mir-4273 ; hsa-mir-4753-3p ; hsa-mir-2117 ; hsa-mir-203a-3p ; hsa-mir-6874-3p ; hsa-mir-148b-5p ; hsa-mir-3168

Nearest miRNA

hsa-mir-101-1/Upstream/376165; hsa-mir-11399/Downstream/7112980;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/28520, chr1-CpG: 89/Downstream/180627

Nearest cancer related gene

SH3GLB1(TSG, No orient, 0)

Upstream sequence

CTGTGGTGGGAGTATTTATA

Junction sequence