Basic Information
VIS ID
TVIS10006389
Fusion event
HBV-chr14 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
1806
Integrated sequence
CCCAAGCGACCCCGAGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCA| |GCCATGGAAACGATGTATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCTAGGAG
Host Sequence
Chromosome
chr14
Cytoband
q21.3
Reference genome
GRCh38
Start
49382149 (Hg38)
End
49382149 (Hg38)
Location type
Intergenic
Nearest miRNA
hsa-mir-208a/Upstream/1621045; hsa-mir-1185-1/Downstream/584250;
Nearest TSS
ENST00000550708/Upstream/304644; ENST00000557531/Downstream/204176;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/1705763, chr14-CpG: 30/Downstream/203783
Nearby gene
RPS29(+194522) ;
Upstream sequence
CCCTATTGACTCCAGT
Junction sequence
CCCTATTGACTCCAGTGCAGACCAATTTATGCCTAC
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Curate