Basic Information
VIS ID
TVIS10006391
Fusion event
HBV-LOC101929622 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
1824
Integrated sequence
GGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAGCCATGGAAACGATGTAT| |ATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCTAGGAGTTCCGCAGTATGGATCGG
Host Sequence
Chromosome
chr8
Cytoband
p11.23
Reference genome
GRCh38
Start
37724134 (Hg38)
End
37724134 (Hg38)
Location type
Intron
Target gene
LOC101929622
Nearest miRNA
hsa-mir-124-1/Upstream/7766786; hsa-mir-10400/Downstream/3546914;
Nearest TSS
ENST00000518652/Upstream/6555; ENST00000519872/Downstream/12465;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/22765, chr8-CpG: 81/Downstream/12182
Downstream sequence
ACTCCAGCCCTCCTCTGAGC
Junction sequence
GCACCAGCACCATGCAACTTACTCCAGCCCTCCTCTGAGC
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Curate