Basic Information
VIS ID
TVIS10006392
Fusion event
HBV-NPSR1-AS1 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Host Sequence
Chromosome
chr7
Cytoband
p14.3
Reference genome
GRCh38
Start
34592630 (Hg38)
End
34592630 (Hg38)
Location type
Intron
Target gene
NPSR1-AS1
Nearest miRNA
hsa-mir-1183/Upstream/1859553; hsa-mir-10399/Downstream/348130;
Nearest TSS
ENST00000635602/Upstream/383104; ENST00000465305/Downstream/65609;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/513483, chr7-CpG: 203/Downstream/443894
Upstream sequence
ctttcttgccctctctctgccctttcaccatggaatgatacagcaaggaaaccctcacaagatgctgataccttgatagtggacttccaaacctacagaa
Downstream sequence
ctgtgagccaataaatttctcttcattataaattatcccaactatggtattctatggtatttacggcagcacaaaacaggataagacaGAAGGGAAAAAA
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Curate