Basic Information
VIS ID
TVIS10006395
Fusion event
HBV-LINC02211 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
1725
Integrated sequence
GGCACAGACGGGGAGTCCGCGTAAAGAGAGGTGCGCCCCGTGGTCGGTCGGAACGGCAGACGGAGAAGGGGACGAGAGAGTCCCAAGCGACCCCGAGAAG| |GGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAGCCATGGAAACGATGTATA
Host Sequence
Chromosome
chr5
Cytoband
p14.1
Reference genome
GRCh38
Start
25236337 (Hg38)
End
25236337 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA5E
Target gene
LINC02211
Nearest miRNA
hsa-mir-10397/Upstream/8080345; hsa-mir-103a-1/Downstream/6699765;
Nearest TSS
ENST00000502646/Upstream/45381; ENST00000641091/Downstream/61397;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/45333, chr5-CpG: 29/Downstream/672896
Nearby gene
LINC02239(-395754) ;
Upstream sequence
ACCCTGTCAACCACTAT
Junction sequence
ACCCTGTCAACCACTATAACAAACAGTCTTTGAAGTA
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Curate