MICAL3 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10006399
Fusion event
HBV-MICAL3 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
1796
Integrated sequence
ACGAGAGAGTCCCAAGCGACCCCGAGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCA| |CAGCCTAGCAGCCATGGAAACGATGTATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAG
Host Sequence
Chromosome
chr22
Cytoband
q11.21
Reference genome
GRCh38
Start
17962139 (Hg38)
End
17962139 (Hg38)
Location type
Intron
Target gene
MICAL3
Nearest miRNA
hsa-mir-3198-1/Upstream/197880; hsa-let-7a-3/Downstream/18729;
Nearest TSS
ENST00000624155/Upstream/55265; ENST00000443243/Downstream/39041;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/120117, chr22-CpG: 145/Downstream/38286
Upstream sequence
CTTGCTGACTGCACATATCACATG
Junction sequence
CTTGCTGACTGCACATATCACATGNCATTTATGCCTACAGCCTCCT
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Curate