ABCC8 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10006400
Fusion event
HBV-ABCC8 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
27453547
Virus Sequence
Virus name
HBV
Reference genome
V01460.1
Start
1802
Integrated sequence
GAGTCCCAAGCGACCCCGAGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCT| |AGCAGCCATGGAAACGATGTATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCTA
Host Sequence
Chromosome
chr11
Cytoband
p15.1
Reference genome
GRCh38
Start
17429330 (Hg38)
End
17429330 (Hg38)
Location type
Intron
Fragile sites / regions
FRA11C ; FRA11I
Target gene
ABCC8
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-136-5p
Nearest miRNA
hsa-mir-210/Upstream/1459709; hsa-let-7a-2/Downstream/958457;
Nearest TSS
ENST00000527297/Upstream/762; ENST00000428619/Downstream/2897;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/39590, chr11-CpG: 93/Downstream/46586
Downstream sequence
ATCCCACCCTCAAGGCAA
Junction sequence
CTGTAGGNNTAAATTGGTCTATCCCACCCTCAAGGCAA
* Color:  Human Sequence / Virus Sequence / Overlapped sequence / Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.
Curate