VISDB Viral Integration Site DataBase

VIS ID

TVIS10006405

Fusion event

HBV-PER2 integration

Validated

Yes

Detection method

invPCR +Sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Perfect

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1813

Integrated sequence

GACCCCGAGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAGCCATGG| |AAACGATGTATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCTAGGAGTTCCGCA

Chromosome

chr2

Cytoband

q37.3

Reference genome

Start

End

238285839 (Hg38)

Location type

Intron

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-24-3p ; hsa-mir-5087 ; hsa-mir-6715a-3p ; hsa-mir-6771-5p ; hsa-mir-425-3p ; hsa-mir-27b-5p ; hsa-mir-6515-3p ; hsa-mir-4699-3p ; hsa-mir-590-5p ; hsa-mir-21-5p ; hsa-mir-5580-3p ; hsa-mir-665 ; hsa-mir-133a-3p ; hsa-mir-7977 ; hsa-mir-4281 ; hsa-mir-7160-5p ; hsa-mir-6811-3p ; hsa-mir-4722-5p ; hsa-mir-6884-5p ; hsa-mir-485-5p ; hsa-mir-1827 ; hsa-mir-4649-3p ; hsa-mir-3664-3p ; hsa-mir-6078 ; hsa-mir-4433a-3p ; hsa-mir-4459 ; hsa-mir-4768-3p ; hsa-mir-5690 ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929 ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-4695-5p ; hsa-mir-510-5p ; hsa-mir-512-5p ; hsa-mir-3187-3p ; hsa-mir-4435 ; hsa-mir-588 ; hsa-mir-4701-5p ; hsa-mir-548s ; hsa-mir-4540 ; hsa-mir-6723-5p ; hsa-mir-6815-3p ; hsa-mir-4653-3p ; hsa-mir-103a-2-5p ; hsa-mir-8082 ; hsa-mir-4534 ; hsa-mir-571 ; hsa-mir-645 ; hsa-mir-6514-5p ; hsa-mir-4715-5p ; hsa-mir-557 ; hsa-mir-507 ; hsa-mir-659-3p ; hsa-mir-29b-2-5p ; hsa-mir-4325 ; hsa-mir-7703 ; hsa-mir-555 ; hsa-mir-8064 ; hsa-mir-6861-5p ; hsa-mir-561-3p ; hsa-mir-186-5p ; hsa-mir-3133 ; hsa-mir-92a-3p ; hsa-mir-25-3p ; hsa-mir-32-5p ; hsa-mir-363-3p ; hsa-mir-92b-3p ; hsa-mir-367-3p ; hsa-mir-495-3p ; hsa-mir-5688 ; hsa-mir-30e-5p ; hsa-mir-30d-5p ; hsa-mir-30c-5p ; hsa-mir-30b-5p ; hsa-mir-181d-5p ; hsa-mir-30a-5p ; hsa-mir-181c-5p ; hsa-mir-181b-5p ; hsa-mir-181a-5p

Nearest miRNA

hsa-mir-10b/Upstream/774851; hsa-mir-149/Downstream/782978;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/44580, chr2-CpG: 128/Downstream/2443

Nearest cancer related gene

PER2(TSG, No orient, 0)

Downstream sequence

AGCCCTGCAGGATTTTACAACC

Junction sequence