VISDB Viral Integration Site DataBase

VIS ID

TVIS10006406

Fusion event

HBV-COL4A4 integration

Validated

Yes

Detection method

invPCR +Sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Perfect

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1824

Integrated sequence

GGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAGCCATGGAAACGATGTAT| |ATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCTAGGAGTTCCGCAGTATGGATCGG

Chromosome

chr2

Cytoband

q36.3

Reference genome

Start

End

227134742 (Hg38)

Location type

Intron

Target gene

miRNAs that regulate target gene

hsa-mir-124-3p ; hsa-mir-26b-5p ; hsa-mir-150-5p ; hsa-mir-4659b-3p ; hsa-mir-4659a-3p ; hsa-mir-6875-3p ; hsa-mir-1257 ; hsa-mir-302d-5p ; hsa-mir-302b-5p ; hsa-mir-4778-3p ; hsa-mir-4302 ; hsa-mir-4753-3p ; hsa-mir-6873-3p ; hsa-mir-130b-5p ; hsa-mir-6817-3p ; hsa-mir-7110-3p ; hsa-mir-216b-5p ; hsa-mir-548c-3p

Nearest miRNA

hsa-mir-10b/Upstream/475949; hsa-mir-1244-1/Downstream/337390;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/298343, chr2-CpG: 53/Downstream/29221

Downstream sequence

GAAAGAATGACTCACTCACG

Junction sequence