Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10006408
Fusion event
HBV-COPG2 integration
Validated
Yes
Detection method
invPCR +Sequencing
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Perfect
Reported year
2016
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
1749
Integrated sequence
AGAGAGGTGCGCCCCGTGGTCGGTCGGAACGGCAGACGGAGAAGGGGACGAGAGAGTCCCAAGCGACCCCGAGAAGGGTCGTCCGCAGGATTCAGCGCCG| |ACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAGCCATGGAAACGATGTATATTTGCGGGATAGGACAACAGAGTT
Host Sequence
Chromosome
chr7
Cytoband
q32.2
Reference genome
Start
End
130562490 (Hg38)
Location type
Intron
Fragile sites / regions
Target gene
Nearest miRNA
hsa-mir-10525/Upstream/66286; hsa-mir-10399/Downstream/314257;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/69220, chr7-CpG: 104/Downstream/105740
Upstream sequence
ATGTATTGCCTATGACAAG
Junction sequence
ATGTATTGCCTATGACAAGTCCCCCAACTCCTCCCNGTC
* Color:
Human Sequence
/
Virus Sequence
/
Overlapped sequence
/
Unknown sequence
Reference
Mason, W. S., et al. HBV DNA Integration and Clonal Hepatocyte Expansion in Chronic Hepatitis B Patients Considered Immune Tolerant. Gastroenterology,2016, 151(5): 986-998 e984.