VISDB Viral Integration Site DataBase

VIS ID

TVIS10006417

Fusion event

HBV-SLC8A1 integration

Validated

Yes

Detection method

invPCR +Sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Perfect

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1827

Integrated sequence

TCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAGCCATGGAAACGATGTATATT| |TGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCTAGGAGTTCCGCAGTATGGATCGGCAG

Chromosome

chr2

Cytoband

p22.1

Reference genome

Start

End

40345643 (Hg38)

Location type

Intron

Target gene

miRNAs that regulate target gene

hsa-mir-1-3p ; hsa-mir-557 ; hsa-mir-507 ; hsa-mir-1273e ; hsa-mir-3924 ; hsa-mir-590-3p ; hsa-mir-190a-3p ; hsa-mir-5011-5p ; hsa-mir-513c-3p ; hsa-mir-513a-3p ; hsa-mir-3606-3p ; hsa-mir-410-3p ; hsa-mir-4699-3p ; hsa-mir-4683 ; hsa-mir-4784 ; hsa-mir-3150b-3p ; hsa-mir-494-3p ; hsa-mir-199b-5p ; hsa-mir-199a-5p ; hsa-mir-1825 ; hsa-mir-6847-5p ; hsa-mir-512-3p ; hsa-mir-6888-5p ; hsa-mir-5693 ; hsa-mir-8057 ; hsa-mir-4423-3p ; hsa-mir-760 ; hsa-mir-6822-3p ; hsa-mir-3135a ; hsa-mir-4766-5p ; hsa-mir-146a-3p ; hsa-mir-3622a-5p ; hsa-mir-5582-5p ; hsa-mir-4775 ; hsa-mir-4668-3p ; hsa-mir-1305 ; hsa-mir-599 ; hsa-mir-3978 ; hsa-mir-3161 ; hsa-mir-6124 ; hsa-mir-4282 ; hsa-mir-3148 ; hsa-mir-501-5p ; hsa-mir-500a-5p ; hsa-mir-185-5p

Nearest miRNA

hsa-mir-1301/Upstream/4874157; hsa-mir-10b/Downstream/7032032;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/566320, chr2-CpG: 16/Downstream/105694

Downstream sequence

TTGAAAACCCTCTATGCAGCC

Junction sequence