VISDB Viral Integration Site DataBase

VIS ID

TVIS10006419

Fusion event

HBV-UGT3A1 integration

Validated

Yes

Detection method

invPCR +Sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Perfect

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1827

Integrated sequence

TCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAGCCATGGAAACGATGTATATT| |TGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCTAGGAGTTCCGCAGTATGGATCGGCAG

Chromosome

chr5

Cytoband

p13.2

Reference genome

Start

End

36000096 (Hg38)

Location type

Intron

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-181a-5p ; hsa-mir-498 ; hsa-mir-513b-5p ; hsa-mir-219a-2-3p ; hsa-mir-219b-3p ; hsa-mir-3156-5p ; hsa-mir-6715b-3p ; hsa-mir-3667-3p ; hsa-mir-6734-3p ; hsa-mir-4272 ; hsa-mir-4802-3p ; hsa-mir-4680-3p

Nearest miRNA

hsa-mir-10397/Upstream/3605621; hsa-mir-103a-1/Downstream/147796;

Nearest TSS

Nearest CpG islands

None/Target, chr5-CpG: 87/Upstream/381859, chr5-CpG: 85/Downstream/151299

Upstream sequence

TGGAGAGGCCCAATGGAAT

Junction sequence