VISDB Viral Integration Site DataBase

VIS ID

TVIS10006423

Fusion event

HBV-chr16 integration

Validated

Yes

Detection method

invPCR +Sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Perfect

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1811

Integrated sequence

GCGACCCCGAGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAGCCAT| |GGAAACGATGTATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCTAGGAGTTCCG

Chromosome

chr16

Cytoband

p13.12

Reference genome

Start

End

13311889 (Hg38)

Location type

Intronic

Target gene

LOC107984137 ; SHISA9

miRNAs that regulate target gene

hsa-mir-4531 ; hsa-mir-7847-3p ; hsa-mir-4764-5p ; hsa-mir-5192 ; hsa-mir-4644 ; hsa-mir-4306 ; hsa-mir-185-5p ; hsa-mir-5703 ; hsa-mir-4516 ; hsa-mir-4434 ; hsa-mir-1287-5p ; hsa-mir-3135b ; hsa-mir-3605-5p ; hsa-mir-764 ; hsa-mir-4657 ; hsa-mir-4491 ; hsa-mir-1265 ; hsa-mir-3914 ; hsa-mir-5096 ; hsa-mir-7641 ; hsa-mir-197-3p ; hsa-mir-4695-3p ; hsa-mir-4716-5p ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929 ; hsa-mir-1911-3p ; hsa-mir-4261 ; hsa-mir-873-5p ; hsa-mir-1285-5p ; hsa-mir-4496 ; hsa-mir-552-3p ; hsa-mir-5197-5p ; hsa-mir-374b-5p ; hsa-mir-374a-5p ; hsa-mir-5692c ; hsa-mir-5692b ; hsa-mir-369-3p ; hsa-mir-508-5p ; hsa-mir-3145-5p ; hsa-mir-548l ; hsa-mir-8054 ; hsa-mir-548k ; hsa-mir-548av-5p ; hsa-mir-559 ; hsa-mir-548y ; hsa-mir-548w ; hsa-mir-548o-5p ; hsa-mir-548j-5p ; hsa-mir-548i ; hsa-mir-548h-5p ; hsa-mir-548d-5p ; hsa-mir-548c-5p ; hsa-mir-548bb-5p ; hsa-mir-548b-5p ; hsa-mir-548ay-5p ; hsa-mir-548au-5p ; hsa-mir-548as-5p ; hsa-mir-548ar-5p ; hsa-mir-548aq-5p ; hsa-mir-548ap-5p ; hsa-mir-548am-5p ; hsa-mir-548ak ; hsa-mir-548ae-5p ; hsa-mir-548ad-5p ; hsa-mir-548ab ; hsa-mir-548a-5p ; hsa-mir-3187-3p ; hsa-mir-653-3p ; hsa-mir-4529-5p ; hsa-mir-6847-3p ; hsa-mir-539-5p ; hsa-mir-3190-5p ; hsa-mir-3919 ; hsa-mir-4756-3p ; hsa-mir-548o-3p ; hsa-mir-5680 ; hsa-mir-1323 ; hsa-mir-193b-3p ; hsa-mir-193a-3p ; hsa-mir-551b-5p ; hsa-mir-497-3p ; hsa-mir-548t-3p ; hsa-mir-548ap-3p ; hsa-mir-548aa ; hsa-mir-7156-3p ; hsa-mir-6516-3p ; hsa-mir-1206 ; hsa-mir-1272 ; hsa-mir-3662 ; hsa-mir-8084 ; hsa-mir-642a-5p ; hsa-mir-6883-3p ; hsa-mir-6515-3p ; hsa-mir-6734-3p ; hsa-mir-877-3p ; hsa-mir-2276-5p ; hsa-mir-6892-3p ; hsa-mir-454-5p ; hsa-mir-4277 ; hsa-mir-584-3p ; hsa-mir-6505-5p ; hsa-mir-4789-5p ; hsa-mir-7153-3p ; hsa-mir-129-5p ; hsa-mir-1304-3p ; hsa-mir-4474-5p ; hsa-mir-483-3p ; hsa-mir-8055

Nearest miRNA

hsa-mir-1225/Upstream/591518; hsa-mir-11401/Downstream/992078;

Nearest TSS

Nearest CpG islands

None/Target, chr16-CpG: 29/Upstream/408056, chr16-CpG: 56/Downstream/608005

Nearby gene

SHISA9(-76479) ; ERCC4(+610142) ;

Downstream sequence

AAAATTAAATGAACTAAAAT

Junction sequence