VISDB Viral Integration Site DataBase

VIS ID

TVIS10006424

Fusion event

HBV-STYK1 integration

Validated

Yes

Detection method

invPCR +Sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Perfect

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1789

Integrated sequence

GAAGGGGACGAGAGAGTCCCAAGCGACCCCGAGAAGGGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTT| |GGCAGCACAGCCTAGCAGCCATGGAAACGATGTATATTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCA

Chromosome

chr12

Cytoband

p13.2

Reference genome

Start

End

10664319 (Hg38)

Location type

Intron

Target gene

miRNAs that regulate target gene

hsa-mir-653-5p ; hsa-mir-610 ; hsa-mir-6857-3p ; hsa-mir-1248 ; hsa-mir-3614-3p ; hsa-mir-4499 ; hsa-mir-7109-3p ; hsa-mir-7161-5p ; hsa-mir-548u ; hsa-mir-8485 ; hsa-mir-5096 ; hsa-mir-653-3p ; hsa-mir-4420 ; hsa-mir-181b-3p ; hsa-mir-181b-2-3p ; hsa-mir-8064 ; hsa-mir-1208 ; hsa-mir-6760-3p ; hsa-mir-627-3p ; hsa-mir-4677-5p ; hsa-mir-4666a-5p ; hsa-mir-22-5p ; hsa-mir-2116-5p

Nearest miRNA

hsa-mir-1244-3/Upstream/1424768; hsa-let-7i/Downstream/1447633;

Nearest TSS

Nearest CpG islands

None/Target, chr12-CpG: 104/Upstream/50587, chr12-CpG: 22/Downstream/9613

Nearest cancer related gene

STYK1(OG, No orient, 0)

Upstream sequence

CACATCCCTAACTTCCTATT

Junction sequence