VISDB Viral Integration Site DataBase

VIS ID

TVIS10006425

Fusion event

HBV-ENAH integration

Validated

Yes

Detection method

invPCR +Sequencing

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Perfect

Reported year

2016

PubMed ID

Virus name

HBV

Reference genome

Start

1825

Integrated sequence

GGTCGTCCGCAGGATTCAGCGCCGACGGGACGTAAACAAAGGACGTCCCGCGCAGGATCCAGTTGGCAGCACAGCCTAGCAGCCATGGAAACGATGTATA| |TTTGCGGGATAGGACAACAGAGTTATCAGTCCCGATAATGTTTGCTCCAGACCTGCTGCGAGCAAAACAAGCGGCTAGGAGTTCCGCAGTATGGATCGGC

Chromosome

chr1

Cytoband

q42.12

Reference genome

Start

End

225490526 (Hg38)

Location type

Intron

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-615-3p ; hsa-mir-375 ; hsa-mir-142-3p ; hsa-mir-124-3p ; hsa-mir-181a-5p ; hsa-mir-21-5p ; hsa-mir-93-3p ; hsa-mir-193b-3p ; hsa-mir-191-5p ; hsa-mir-196a-5p ; hsa-mir-4282 ; hsa-mir-219b-5p ; hsa-mir-3145-3p ; hsa-mir-548c-3p ; hsa-mir-4452 ; hsa-mir-183-3p ; hsa-mir-203a-3p ; hsa-mir-5680 ; hsa-mir-3200-5p ; hsa-mir-590-3p ; hsa-mir-618 ; hsa-mir-548p ; hsa-mir-2278 ; hsa-mir-665 ; hsa-mir-1273e ; hsa-mir-211-5p ; hsa-mir-204-5p ; hsa-mir-7160-5p ; hsa-mir-873-5p ; hsa-mir-1827 ; hsa-mir-4649-3p ; hsa-mir-6832-3p ; hsa-mir-6866-3p ; hsa-mir-188-5p ; hsa-mir-4478 ; hsa-mir-3929 ; hsa-mir-4419b ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-6854-3p ; hsa-mir-629-3p ; hsa-mir-548aw ; hsa-mir-4279 ; hsa-mir-6881-3p ; hsa-mir-1468-3p ; hsa-mir-548x-5p ; hsa-mir-548g-5p ; hsa-mir-548f-5p ; hsa-mir-548aj-5p ; hsa-mir-877-3p ; hsa-mir-7109-3p ; hsa-mir-5582-3p ; hsa-mir-548x-3p ; hsa-mir-548j-3p ; hsa-mir-548aq-3p ; hsa-mir-548am-3p ; hsa-mir-548aj-3p ; hsa-mir-548ah-3p ; hsa-mir-548ae-3p ; hsa-mir-3613-3p ; hsa-mir-6848-3p ; hsa-mir-6843-3p ; hsa-mir-378a-5p ; hsa-mir-6131 ; hsa-mir-6821-3p ; hsa-mir-6790-3p ; hsa-mir-18a-3p ; hsa-mir-324-3p ; hsa-mir-1913 ; hsa-mir-3653-5p ; hsa-mir-372-5p ; hsa-mir-371a-5p ; hsa-mir-3934-5p ; hsa-mir-764 ; hsa-mir-125a-3p ; hsa-mir-548s ; hsa-mir-3926 ; hsa-mir-4786-5p ; hsa-mir-3190-5p ; hsa-mir-6849-3p ; hsa-mir-323b-3p ; hsa-mir-433-5p ; hsa-mir-488-3p ; hsa-mir-6815-3p ; hsa-mir-103a-2-5p ; hsa-mir-4778-3p ; hsa-mir-6837-3p ; hsa-mir-6754-3p ; hsa-mir-412-3p ; hsa-mir-3158-3p ; hsa-mir-3154

Nearest miRNA

hsa-mir-101-1/Upstream/1092215; hsa-mir-1182/Downstream/431554;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/15187, chr1-CpG: 168/Downstream/162042

Downstream sequence

ATCGCACCACTGCACTCC

Junction sequence